A new study has found that people who begin taking anti-anxiety medications such as Xanax, Ativan or Valium after the age of 65 have a 50 percent greater chance of developing dementia within 15 years than people who have never taken this class of drugs.
The researchers used the first five years to identify the factors leading to the first prescription for a benzodiazepine medication, then evaluated the association between the new use of this drug and the development of dementia. They also assessed the association between further benzodiazepine drug use during the follow-up period and risk of subsequent dementia.
Researchers carried out a study on 1,063 men and women with an average age 78 in France who were all free of dementia at the start of the study in 1987, with a planned follow-up in 20 years.
They say that their findings add to the accumulating evidence that the use of these drugs is associated with increased risk of dementia and, if true, that this “would constitute a substantial public health concern.”
The researchers note that while many of the benzodiazepine medications remain useful for treating anxiety and insomnia, there is increasing evidence that their use may induce adverse outcomes in the elderly, such as serious falls, fall-related fractures and, now, dementia.
In fact, according to the CDC, 64–79% of people over the age of 65 have it. medications such as Ativan (lorazepam) and Xanax (alprazolam).
Thankfully, a database developed by the American Geriatrics Society (AGS) aims to prevent bad drug interactions and side effects in those over the age of 65 by flagging drugs that are inappropriate for older people. The challenge is getting doctors to use it.
Third is the simple fact that older people take so many more drugs than younger people. More drugs in the body means more risk.
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Are you concerned about side effects with Xanax? of benzodiazepines, and in general, they should be avoided those over 65 years of age.
Doses range from 0.25 milligram (mg) to 0.5 mg tablets, usually given three times day, although your doctor may adjust this based on your individual symptoms.
Plasma levels are proportionate to the dose given; over the dose range of 0.5 to 3.0 mg,.. when alprazolam was given, especially in elderly (>65 years of age).
Relapse or return of illness was defined as a return of symptoms characteristic of panic disorder (primarily panic attacks) to levels approximay equal to those seen at baseline before active treatment was initiated. Rebound refers to a return of symptoms of panic disorder to a level substantially greater in frequency, or more severe in intensity than seen at baseline. Withdrawal symptoms were identified as those which were generally not characteristic of panic disorder and which occurred for the first time more frequently during discontinuation than at baseline.
Benzodiazepines can potentially cause fetal harm when administered to pregnant women.
Alprazolam (Oral Route) Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. The effects may be increased because of slower removal of the medicine from the.
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Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you.