Nabumetone belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Other members of this class include ibuprofen (Motrin), indomethacin (Indocin), naproxen (Aleve) and several others. Nabumetone, Relafen (Discontinued) is a drug prescribed to treat.
Black, tarry stools, weakness, and dizziness upon standing may be the only signs of internal bleeding. Some studies have shown that nabumetone may have a lower risk of gastrointestinal side effects than the other NSAID medications. Sometimes ulceration and bleeding can occur without any abdominal pain.
NSAIDs block the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. These drugs are used for the management of mild to moderate pain, fever, and inflammation.
Learn about Relafen (Nabumetone) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications.
To minimize the potential risk for an adverse GI event in patients treated with an NSAID, the lowest effective dose should be used for the shortest possible duration. For high risk patients, alternate therapies that do not involve NSAIDs should be considered. This should include discontinuation of the NSAID until a serious GI adverse event is ruled out. Patients and physicians should remain alert for signs and symptoms of GI ulceration and bleeding during NSAID therapy and promptly initiate additional evaluation and treatment if a serious GI adverse event is suspected.
Tablets: Oval-shaped, film-coated: 500 mg-white, imprinted with the product name RELAFEN (nabumetone) and 500, in bottles of 100, and in Single-Unit Packages of 100 (intended for institutional use only).
Find a comprehensive guide to possible side effects including common and rare side effects when taking Relafen (Nabumetone) for healthcare professionals.
oval, white, imprinted with IG, 257.
Read the entire detailed patient monograph for Relafen (Nabumetone).
Medical Editor: John P. Cunha, DO, FACOEP.
oblong, white, imprinted with RELAFEN, 500.
oblong, beige, imprinted with 93, 16.
Gastrointestinal : Bilirubinuria, duodenitis, eructation, gallstones, gingivitis, glossitis, pancreatitis, rectal bleeding. Central Nervous System : Nightmares. Dermatologic : Acne, alopecia. Cardiovascular : Angina, arrhythmia, hypertension, myocardial infarction, palpitations, syncope, thrombophlebitis.
Find patient medical information for Nabumetone Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.Information last revised July 2018. 2018 First Databank, Inc. Find Related Drugs.
Kidney problems can sometimes occur with the use of NSAID medications, including nabumetone. Problems are more likely to occur if you are dehydrated, have heart failure or kidney disease, are an older adult, or if you take certain medications (see also Drug Interactions section).
Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID). Nabumetone has been developed by Beecham. It is available under numerous brand names.
It has been shown to have a slightly lower risk of gastrointestinal side effects than most other non-selective NSAIDs since it is a non-acidic prodrug which is then metabolized to its active 6MNA (6-methoxy-2-naphthylacetic acid) form. [ citation needed ]
Similar in action to other NSAIDs, Nabumetone is used to treat pain and inflammation. [ citation needed ]
Nabumetone is a nonacidic NSAID that is rapidly metabolized in the liver to a major active metabolite, 6-methoxy-2-naphthyl acetic acid.