Atenolol (Tenormin) Side Effects, Dosages, Treatment, Interactions

11.20.2018 by Isaac Mercer
Atenolol (Tenormin) Side Effects, Dosages, Treatment, Interactions

Atenolol has moderate interactions with at least 175 different drugs.

What Other Drugs Interact with Atenolol?

Atenolol. SOURCE: Medscape.

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Avoid abrupt withdrawal; sudden discontinuance can exacerbate angina and lead to MI.

This medication contains atenolol. Do not take Tenormin if you are allergic to atenolol or any ingredients contained in this drug.

What Are Side Effects Associated with Using Atenolol?

Ischemic heart disease may be exacerbated after abrupt withdrawal.

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May cause or exacerbate CNS depression (use with caution in patients with psychiatric illness).

Avoid beta-blockers without alpha1-adrenergic receptor blocking activity in patients with Prinzmetal variant angina ; unopposed alpha1-adrenergic receptors mediate coronary vasoconstriction and can worsen anginal symptoms.

This medication is also used to treat chest pain ( angina ) and to improve survival after a heart attack. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Atenolol is used with or without other medications to treat high blood pressure ( hypertension ).

If your doctor has directed you to use this medication for diabetes, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Use with caution in anesthesia or surgery (myocardial depression), bronchospastic disease, cerebrovascular insufficiency, diabetes mellitus, hyperthyroidism or thyrotoxicosis, liver disease, renal impairment, peripheral vascular disease, compromised left ventricular function, advanced age, heart failure.

Adult: 50 mg/day orally; after 1 week, may be increased to 100 mg/day orally; some patients may require 200 mg/day.

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CrCl greater than 35 mL/min/1.73 m²: Dose adjustment not necessary.

Atenolol has mild interactions with at least 40 different drugs.

Consider preexisting conditions such as sick sinus syndrome before initiating therapy.

Monitor for worsening of heart failure symptoms in patients with compensated heart failure.

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If angina worsens markedly or acute coronary insufficiency develops, beta-blocker administration should be promptly reinitiated, at least temporarily (in addition to other measures appropriate for unstable angina).

Geriatric: 25 mg/day orally initially; may be increased to 100 mg/day orally.

Other side effects of atenolol include:

Geriatric: 25 mg/day orally; after 1 week, may be increased to 100 mg/day; some patients may require 200 mg/day Secondary prevention.

Adult: 100 mg orally once daily or divided every 12 hours for 6-9 days after myocardial infarction ( MI ).

Atenolol enters breast milk ; neonates born to mothers who are receiving atenolol at parturition or breastfeeding may be at risk for hypoglycemia and bradycardia; use with caution if breastfeeding.

May potentiate hypoglycemia and may mask its signs and symptoms in patients with diabetes mellitus; use caution.

Because coronary artery disease ( CAD ) is common and may be unrecognized, beta-blocker therapy must be discontinued slowly, even in patients treated only for hypertension.

Side effects of atenolol include:

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Use in pheochromocytoma (alpha blockade required before use of beta blocker ).

Use caution in patients with myasthenia gravis ; may precipitate or aggravate symptoms or arterial insufficiency in patients with Raynaud's disease and peripheral vascular disease; use caution and monitor for progression of arterial obstruction.

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Hypersensitivity to catecholamines has been observed during withdrawal.

Increased risk of stroke after surgery.

In patients receiving clonidine, atenolol should be discontinued several days before withdrawal of clonidine.

It works by blocking the action of certain natural chemicals in your body, such as epinephrine, on the heart and blood vessels. This effect lowers the heart rate, blood pressure, and strain on the heart. Atenolol belongs to a class of drugs known as beta-blockers.

50 mg/day orally, beginning up to 3 days before surgery and continued until 7 days after surgery; may be increased to 100 mg/day.

CrCl 15-35 mL/min/1.73 m²: Not to exceed 50 mg/day orally.

25-100 mg orally once daily or divided every 12 hours.

May mask effects of hyperthyroidism.

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Geriatric: 100 mg orally once daily or divided every 12 hours for 6-9 days after MI 50-100 mg/day orally Prevention.

In case of overdose, get medical help or contact a Poison Control Center immediay. Keep out of reach of children.

What Are Warnings and Precautions for Atenolol?

Use with caution in patients taking calcium -channel blockers or cardiac glycosides or using inhaled anesthetics.

Geriatric: May be necessary to initiate dosing at 25 mg/day orally.

CrCl less than 15 mL/min/1.73 m²: Not to exceed 25 mg/day orally.

There are no known severe reactions with the use of atenolol.

Atenolol may also be used to treat irregular heartbeat, heart failure, alcohol withdrawal symptoms, and to prevent migraine headaches.

Adult: 25-50 mg/day orally initially; may be increased to 100 mg/day orally.

Pediatric (Off-label): 0.5-1 mg/kg/day orally; not to exceed 2 mg/kg/day or 100 mg/day.

There is positive evidence of human fetal risk. Use atenolol during pregnancy only in LIFE-THREATENING emergencies when no safer drug available.

Atenolol has serious interactions with at least 21 different drugs.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Patients should be warned against interruption or discontinuance of beta-blocker therapy without physician advice.

Atenolol is available under the following different brand names: Tenormin. Tablet.

Risk of hypoglycemia and bradycardia in neonates born to mothers who receive the drug at parturition or while breastfeeding, especially in premature infants and those with renal impairment.

When long-term beta-blocker therapy (particularly with ischemic heart disease ) is discontinued, dosage should be gradually reduced over 1-2 weeks with careful monitoring.

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Exacerbation of angina and, in some cases, myocardial infarction (MI) may occur after abrupt discontinuance.

Exacerbation or induction of psoriasis reported with beta-blocker use; cause and effect not established.

See "What Are Side Effects Associated with Using Atenolol?".

2°/3° heart block in patients without pacemaker Cardiogenic shock Sinus bradycardia Sinus node dysfunction Hypersensitivity Uncompensated cardiac failure Pulmonary edema None.

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Therefore, before using this product, l your doctor or pharmacist of all the products you use. This document does not contain all possible interactions. Check with your physician if you have health questions or concerns. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

What Is Atenolol and How Does It Work?

See "What Are Side Effects Associated with Using Atenolol?".

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