Topihealsen.biz

Diazepam Side Effects, Dosages, Treatment, Interactions, Warnings


10.26.2018 by Thomas Addington

See additional information. 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment.

Diazepam
Diazepam Side Effects, Dosages, Treatment, Interactions, Warnings

What Are Side Effects Associated with Using Diazepam?

Side effects of diazepam include:

Use with caution in patients with a history of drug abuse or acute alcoholism ; tolerance, psychological, and physical dependence may occur with prolonged use (greater than 10 days).

It belongs to a class of drugs known as benzodiazepines. Diazepam works by calming the brain and nerves.

Drug Interaction Tool Check Potential Drug Interactions.

0.5 mg/kg rectally (using parenteral solution), THEN 0.25 mg/kg in 10 minutes as needed.

Anterograde amnesia reported with benzodiazepine use.

Potentially toxic dose in patients under 6 years: greater than 0.5 mg/kg.

Diazepam has moderate interactions with at least 46 different drugs.

Diazepam is not recommended for children younger than 6 months of age because of the risk of serious side effects.

Avoid extravasation with intravenous (IV) dosing.

Diazepam. https://reference.medscape.com/drug/valium-diastat-diazepam-342902. SOURCE: Medscape.

Advise both patients and caregivers about risks of respiratory depression and sedation when diazepam is used with opioids; advise patients not to drive or operate heavy machinery until the effects of concomitant use with the opioid have been determined.

Pharmacy Locater Tool Including 24 Hour, Pharmacies.

2-10 mg orally every 6-12 hours, OR 2-10 mg intravenously/intramuscularly (IV/IM) every 6-12 hours; no more than 30 mg/8 hours.

Diazepam has moderate interactions with at least 238 different drugs.

Rectal gel: Use lower dose.

What Other Drugs Interact with Diazepam?

Documented hypersensitivity Acute alcohol intoxication. In case of overdose, get medical help or contact a Poison Control Center immediay. Keep out of reach of children.

Hepatic impairment: 50% of maintenance dose Geriatric:

Adult: 5-10 mg IV/IM every 5-10 minutes; not to exceed 30 mg, OR.

Tips to Fast Stress Relief.

Acute narrow angle glaucoma and open angle glaucoma unless patients receiving appropriate therapy Severe respiratory depression.

Do not take Valium, Diastat, or Diastat AcuDial if you are allergic to diazepam or any ingredients contained in this drug. This medication contains diazepam.

Tablet : Schedule IV.

See "What Are Side Effects Associated with Using Diazepam?".

Postmarketing side effects of diazepam reported include:

What Are Warnings and Precautions for Diazepam?

2-10 mg orally every 6-12 hours as adjunct, OR.

Intravenously (IV): Titrate dose to 10 mg or less immediay before procedure, not to exceed cumulative dose of 20 mg; reduce dose of narcotic by one third or omit, OR.

Uncontrolled seizures can turn into serious (possibly fatal) seizures that do not stop ( status epilepticus ). Diazepam is used to treat episodes of increased seizures (such as cluster or breakthrough seizures) in people who are already taking medications to control their seizures. It is not for ongoing daily use to prevent seizures. This product is only recommended for short-term treatment of seizure attacks.

See "What Are Side Effects Associated with Using Diazepam?".

Intramuscularly (IM): 5-10 mg 30 minutes before procedure.

Use with caution in patients with a history of drug abuse or acute alcoholism; tolerance, psychological, and physical dependence may occur with prolonged use (greater than 10 days).

Use caution in COPD, sleep apnea, renal/hepatic disease, open-angle glaucoma (questionable), depression, suicide ideation, impaired gag reflex, history of drug abuse, or obese patients (prolonged action when discontinued).

Injury, poisoning and procedural complications: Falls and fractures; increased risk in those taking concomitant sedatives (including alcoholic beverages) and in the elderly, suicide attempt, suicidal ideation.

Pediatric : Potentially toxic dose in patients under 6 years: greater than 0.5 mg/kg Rectally Intravenously (IV).

This document does not contain all possible interactions. Therefore, before using this product, l your doctor or pharmacist of all the products you use. Check with your physician if you have health questions or concerns. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Prenatal benzodiazepine exposure slightly increased oral cleft risk (limited or inconsistent evidence). Maternal use shortly before delivery is associated with floppy infant syndrome (good and consistent evidence).

Children under 6 months.

5-10 mg intravenously (IV) 1-2 hours before surgery; 0.03-0.1 mg/kg every 30 minutes to 6 hours.

Diazepam is available under the following different brand names: Valium, Diastat, and Diastat AcuDial.

Pill Identifier Tool Quick, Easy, Pill Identification.

Renal impairment: No dose adjustment recommended unless administered for prolonged period; decrease dose in prolonged periods.

May impair ability to perform hazardous tasks.

Serious side effects of diazepam include:

Intramuscular device: Schedule IV.

Drug interaction overview:. Abrupt withdrawal may result in temporary increase of seizures.

Children over 12 years.

10 mg intramuscularly (IM) before surgery.

Administration for prolonged periods of time may lead to drug dependence and must be avoided.

0.2 mg/kg rectally, repeat after 4-12 hours as needed.

Generalized Anxiety Disorder (GAD) Slideshow.

home > diazepam article.

If your doctor has directed you to use this medication for diabetes, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Serious Interactions of diazepam include:

Diazepam enters breast milk ; it is not recommended for use while breastfeeding.

Rectal gel: Schedule IV.

Children under 6 months: Not recommended.

10 mg orally every 6-8 hours during first 24 hours; reduce to 5 mg orally every 6-8 hours as needed.

Intravenous (IV) use in shock, coma, depressed respiration, patients who recently received other respiratory depressants Sleep apnea.

Heart muscle disease ( cardiomyopathy ) (isolated reports associated with chronic use).

Initial: 10 mg intravenously/intramuscularly (IV/IM), may give additional doses of 5-10 mg IV every 6-8 hours as needed.

Tips to Fast Stress Relief.

Due to long-acting metabolite, not considered a drug of choice in the elderly; associated with falls.

Advise both patients and caregivers about risks of respiratory depression and sedation when diazepam is used with opioids; advise patients not to drive or operate heavy machinery until the effects of concomitant use with the opioid have been determined.

Use diazepam during pregnancy only in LIFE-THREATENING emergencies when no safer drug is available. There is positive evidence of human fetal risk. Minor tranquilizers should be avoided in first trimester of pregnancy due to increased risk of congenital malformations.

Injectable solution: Schedule IV.

Concomitant use of benzodiazepines, including diazepam, and opioids may result in profound sedation, respiratory depression, coma, and death; reserve concomitant prescribing of benzodiazepines and opioids for use in patients for whom alternative treatment options are inadequate; reduce opiate dose one-third when diazepam is added.

Paradoxical reactions may occur including hallucinations, aggressive behavior, and psychoses; discontinue use if reactions occur.

Use of benzodiazepines, including diazepam, both used alone and in combination with other CNS depressants, may lead to potentially fatal respiratory depression.

Myasthenia gravis (allowable in limited circumstances).

Take the Panic Attacks Quiz!

Risks from concomitant use with opioids.

Generalized Anxiety Disorder (GAD) Slideshow.

Take the Panic Attacks Quiz!

2-10 mg orally every 6-8 hours as needed, OR 5-10 mg IV/IM initially; THEN every 3-4 hours if necessary.

Oral solution: Schedule IV.

What Is Diazepam and How Does It Work?

2-2.5 mg orally once/day or every 12 hours initially; increase gradually as needed.

Diazepam